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Altered GABAergic markers, increased binocularity and reduced plasticity in the visual cortex of Engrailed-2 knockout mice
The maturation of the GABAergic system is a crucial determinant of cortical development during early postnatal life, when sensory circuits undergo a process of activity-dependent refinement. An altered excitatory/inhibitory balance has been proposed as a possible pathogenic mechanism of autism spect...
Autores principales: | Allegra, Manuela, Genovesi, Sacha, Maggia, Marika, Cenni, Maria C., Zunino, Giulia, Sgadò, Paola, Caleo, Matteo, Bozzi, Yuri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060086/ https://www.ncbi.nlm.nih.gov/pubmed/24987331 http://dx.doi.org/10.3389/fncel.2014.00163 |
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