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Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells
BACKGROUND: Fatty acid synthase (FAS) has been proven over-expressed in human breast cancer cells and consequently, has been recognized as a target for breast cancer treatment. Alpha-mangostin, a natural xanthone found in mangosteen pericarp, has a variety of biological activities, including anti-ca...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060095/ https://www.ncbi.nlm.nih.gov/pubmed/24894151 http://dx.doi.org/10.1186/1476-4598-13-138 |