Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma

RNA interference (RNAi) allows the specific knockdown of tumor relevant genes. To induce RNAi, the delivery of small interfering RNAs (siRNAs) is of crucial importance. This is particularly challenging for their therapeutic applications in vivo. Low molecular weight branched polyethylenimine (PEI) i...

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Detalles Bibliográficos
Autores principales: Höbel, Sabrina, Appeldoorn, Chantal C.M., Gaillard, Pieter J., Aigner, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060103/
https://www.ncbi.nlm.nih.gov/pubmed/27721338
http://dx.doi.org/10.3390/ph4121591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060103/
https://www.ncbi.nlm.nih.gov/pubmed/27721338
http://dx.doi.org/10.3390/ph4121591

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