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Lipothioureas as Lipids for Gene Transfection: A Review

Non-viral gene therapy requires innovative strategies to achieve higher transfection efficacy. A few years ago, our group proposed bioinspired lipids whose interaction with DNA was not based on ionic interactions, but on hydrogen bonds. We thus developed lipids bearing a thiourea head which allowed...

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Detalles Bibliográficos
Autores principales: Breton, Marie, Leblond, Jeanne, Tranchant, Isabelle, Scherman, Daniel, Bessodes, Michel, Herscovici, Jean, Mignet, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060130/
https://www.ncbi.nlm.nih.gov/pubmed/27721329
http://dx.doi.org/10.3390/ph4101381