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Aging Leads to Elevation of O-GlcNAcylation and Disruption of Mitochondrial Homeostasis in Retina

Retina is particularly susceptible to aging as oxidative damage accumulates within retina, leading to age-related retinal dysfunction or even visual loss. However, the underlying mechanisms still remain obscure and effective therapeutic strategy is urgently in need. Here, we quested for the answer p...

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Detalles Bibliográficos
Autores principales: Zhao, Lin, Feng, Zhihui, Zou, Xuan, Cao, Ke, Xu, Jie, Liu, Jiankang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060167/
https://www.ncbi.nlm.nih.gov/pubmed/24987494
http://dx.doi.org/10.1155/2014/425705