CD4(+)CD25(+/high)CD127(low/-) regulatory T cells are enriched in rheumatoid arthritis and osteoarthritis joints—analysis of frequency and phenotype in synovial membrane, synovial fluid and peripheral blood

INTRODUCTION: CD4(+)CD25(+/high)CD127(low/-) regulatory T cells (Tregs) play a crucial role in maintaining peripheral tolerance. Data about the frequency of Tregs in rheumatoid arthritis (RA) are contradictory and based on the analysis of peripheral blood (PB) and synovial fluid (SF). Because Tregs...

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Detalles Bibliográficos
Autores principales: Moradi, Babak, Schnatzer, Philipp, Hagmann, Sébastien, Rosshirt, Nils, Gotterbarm, Tobias, Kretzer, Jan Philippe, Thomsen, Marc, Lorenz, Hanns-Martin, Zeifang, Felix, Tretter, Theresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060198/
https://www.ncbi.nlm.nih.gov/pubmed/24742142
http://dx.doi.org/10.1186/ar4545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060198/
https://www.ncbi.nlm.nih.gov/pubmed/24742142
http://dx.doi.org/10.1186/ar4545

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