Cargando…
CD4(+)CD25(+/high)CD127(low/-) regulatory T cells are enriched in rheumatoid arthritis and osteoarthritis joints—analysis of frequency and phenotype in synovial membrane, synovial fluid and peripheral blood
INTRODUCTION: CD4(+)CD25(+/high)CD127(low/-) regulatory T cells (Tregs) play a crucial role in maintaining peripheral tolerance. Data about the frequency of Tregs in rheumatoid arthritis (RA) are contradictory and based on the analysis of peripheral blood (PB) and synovial fluid (SF). Because Tregs...
Autores principales: | Moradi, Babak, Schnatzer, Philipp, Hagmann, Sébastien, Rosshirt, Nils, Gotterbarm, Tobias, Kretzer, Jan Philippe, Thomsen, Marc, Lorenz, Hanns-Martin, Zeifang, Felix, Tretter, Theresa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060198/ https://www.ncbi.nlm.nih.gov/pubmed/24742142 http://dx.doi.org/10.1186/ar4545 |
Ejemplares similares
-
Synovial Cytokines Significantly Correlate with Osteoarthritis-Related Knee Pain and Disability: Inflammatory Mediators of Potential Clinical Relevance
por: Nees, Timo A., et al.
Publicado: (2019) -
Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis
por: Rosshirt, Nils, et al.
Publicado: (2021) -
Mesenchymal Stromal Cells from Osteoarthritic Synovium Are a Distinct Population Compared to Their Bone-Marrow Counterparts regarding Surface Marker Distribution and Immunomodulation of Allogeneic CD4+ T-Cell Cultures
por: Hagmann, Sebastien, et al.
Publicado: (2016) -
T Helper Cell Infiltration in Osteoarthritis-Related Knee Pain and Disability
por: Nees, Timo Albert, et al.
Publicado: (2020) -
CD14+ monocytes and soluble CD14 of synovial fluid are associated with osteoarthritis progression
por: Lee, Ha-Reum, et al.
Publicado: (2022)