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Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis

Insulin signaling in the central nervous system (CNS) regulates energy balance and peripheral glucose homeostasis. Rictor is a key regulatory/structural subunit of the mTORC2 complex and is required for hydrophobic motif site phosphorylation of Akt at serine 473. To examine the contribution of neuro...

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Detalles Bibliográficos
Autores principales: Kocalis, Heidi E., Hagan, Scott L., George, Leena, Turney, Maxine K., Siuta, Michael A., Laryea, Gloria N., Morris, Lindsey C., Muglia, Louis J., Printz, Richard L., Stanwood, Gregg D., Niswender, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060224/
https://www.ncbi.nlm.nih.gov/pubmed/24944899
http://dx.doi.org/10.1016/j.molmet.2014.01.014