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Anti-inflammatory properties of a dual PPARgamma/alpha agonist muraglitazar in in vitro and in vivo models

INTRODUCTION: Peroxisome proliferator-activated receptor (PPAR) agonists are widely used drugs in the treatment of diabetes and dyslipidemia. In addition to their metabolic effects, PPAR isoforms PPARα and PPARγ are also involved in the regulation of immune responses and inflammation. In the present...

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Detalles Bibliográficos
Autores principales: Paukkeri, Erja-Leena, Leppänen, Tiina, Lindholm, Mira, Yam, Mun Fei, Asmawi, Mohd Zaini, Kolmonen, Anne, Aulaskari, Paula H, Moilanen, Eeva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060226/
https://www.ncbi.nlm.nih.gov/pubmed/23594962
http://dx.doi.org/10.1186/ar4211