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Angiotensin receptor type 1 and endothelin receptor type A on immune cells mediate migration and the expression of IL-8 and CCL18 when stimulated by autoantibodies from systemic sclerosis patients

INTRODUCTION: Agonistic autoantibodies (Aabs) against the angiotensin II receptor type 1 (AT1R) and the endothelin receptor type A (ETAR) have been identified in patients with systemic sclerosis (SSc). In our present study, we examined the expression of the AT1R and the ETAR in human immune cells an...

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Detalles Bibliográficos
Autores principales: Günther, Jeannine, Kill, Angela, Becker, Mike Oliver, Heidecke, Harald, Rademacher, Judith, Siegert, Elise, Radić, Mislav, Burmester, Gerd-Rüdiger, Dragun, Duska, Riemekasten, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060229/
https://www.ncbi.nlm.nih.gov/pubmed/24612997
http://dx.doi.org/10.1186/ar4503