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Accelerated and increased joint damage in young mice with global inactivation of mitogen-inducible gene 6 after ligament and meniscus injury

INTRODUCTION: Ligament and meniscal damage can cause joint disease. Arthritic joints contain increased amounts of epidermal growth factor receptor (EGFR) protein, and polymorphisms in EGFR are associated with arthritis risk. The role of endogenous EGFR regulation during joint disease due to ligament...

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Detalles Bibliográficos
Autores principales: Joiner, Danese M, Less, Kennen D, Van Wieren, Emily M, Zhang, Yu-Wen, Hess, Daniel, Williams, Bart O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060238/
https://www.ncbi.nlm.nih.gov/pubmed/24670222
http://dx.doi.org/10.1186/ar4522