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Tumor Endothelium FasL Establishes a Selective Immune Barrier Promoting Tolerance in Tumors

We describe a novel mechanism regulating the tumor endothelial barrier and T cell homing to tumors. Selective expression of the death mediator Fas ligand (FasL/CD95L) was detected in the vasculature of many human and mouse solid tumors but not in normal vasculature, and in these tumors it was associ...

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Detalles Bibliográficos
Autores principales:	Motz, Gregory T., Santoro, Stephen P., Wang, Li-Ping, Garrabrant, Tom, Lastra, Ricardo R., Hagemann, Ian S., Lal, Priti, Feldman, Michael D., Benencia, Fabian, Coukos, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060245/ https://www.ncbi.nlm.nih.gov/pubmed/24793239 http://dx.doi.org/10.1038/nm.3541

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