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Adenosine A(2A )receptors promote collagen production by a Fli1- and CTGF-mediated mechanism
INTRODUCTION: Adenosine, acting through the A(2A )receptor, promotes tissue matrix production in the skin and the liver and induces the development of dermal fibrosis and cirrhosis in murine models. Since expression of A(2A )receptors is increased in scleroderma fibroblasts, we examined the mechanis...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060252/ https://www.ncbi.nlm.nih.gov/pubmed/23663495 http://dx.doi.org/10.1186/ar4229 |