Cargando…
Adenosine A(2A )receptors promote collagen production by a Fli1- and CTGF-mediated mechanism
INTRODUCTION: Adenosine, acting through the A(2A )receptor, promotes tissue matrix production in the skin and the liver and induces the development of dermal fibrosis and cirrhosis in murine models. Since expression of A(2A )receptors is increased in scleroderma fibroblasts, we examined the mechanis...
Autores principales: | Chan, Edwin SL, Liu, Hailing, Fernandez, Patricia, Luna, Alex, Perez-Aso, Miguel, Bujor, Andreea M, Trojanowska, Maria, Cronstein, Bruce N |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060252/ https://www.ncbi.nlm.nih.gov/pubmed/23663495 http://dx.doi.org/10.1186/ar4229 |
Ejemplares similares
-
Fli1 Downregulation in Scleroderma Myeloid Cells Has Profibrotic and Proinflammatory Effects
por: Bujor, Andreea M., et al.
Publicado: (2020) -
The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin
por: Feig, Jessica L., et al.
Publicado: (2017) -
Adenosine receptors and fibrosis: a translational review
por: Cronstein, Bruce N.
Publicado: (2011) -
Regulation of Inflammation by Adenosine
por: Haskó, György, et al.
Publicado: (2013) -
Adenosine Receptors and Wound Healing
por: Cronstein, Bruce N.
Publicado: (2004)