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High levels of memory B cells are associated with response to a first tumor necrosis factor inhibitor in patients with rheumatoid arthritis in a longitudinal prospective study

INTRODUCTION: Tumor necrosis factor inhibitor (TNFi) therapy is effective for rheumatoid arthritis (RA). Some researchers have suggested that TNFi therapy affects B-cell homeostasis. We studied the effect of TNFi therapy on the distribution of peripheral B-cell subsets to elucidate B-cell–related bi...

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Detalles Bibliográficos
Autores principales: Daien, Claire I, Gailhac, Sarah, Mura, Thibault, Combe, Bernard, Hahne, Michael, Morel, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060280/
https://www.ncbi.nlm.nih.gov/pubmed/24735586
http://dx.doi.org/10.1186/ar4543