First report of in vitro selection of RNA aptamers targeted to recombinant Loxosceles laeta spider toxins

BACKGROUND: Loxoscelism is the envenomation caused by the bite of Loxosceles spp. spiders. It entails severe necrotizing skin lesions, sometimes accompanied by systemic reactions and even death. There are no diagnostic means and treatment is mostly palliative. The main toxin, found in several isofor...

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Detalles Bibliográficos
Autores principales: Sapag, Amalia, Salinas-Luypaert, Catalina, Constenla-Muñoz, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060373/
https://www.ncbi.nlm.nih.gov/pubmed/25027855
http://dx.doi.org/10.1186/0717-6287-47-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060373/
https://www.ncbi.nlm.nih.gov/pubmed/25027855
http://dx.doi.org/10.1186/0717-6287-47-2

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