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Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes
INTRODUCTION: Synovial macrophages, which can release proinflammatory factors, are responsible for the upregulation of cartilage-breakdown proteases and play critical roles in cartilage degradation during the progression of osteoarthritis (OA). In addition, shear stress exerts multifunctional effect...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060380/ https://www.ncbi.nlm.nih.gov/pubmed/23597113 http://dx.doi.org/10.1186/ar4215 |