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Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes

INTRODUCTION: Synovial macrophages, which can release proinflammatory factors, are responsible for the upregulation of cartilage-breakdown proteases and play critical roles in cartilage degradation during the progression of osteoarthritis (OA). In addition, shear stress exerts multifunctional effect...

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Detalles Bibliográficos
Autores principales: Yeh, Chih-Chang, Chang, Shun-Fu, Huang, Ting-Ying, Chang, Hsin-I, Kuo, Hsing-Chun, Wu, Yi-Chien, Hsieh, Ching-Hsiang, Shi, Chung-Sheng, Chen, Cheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060380/
https://www.ncbi.nlm.nih.gov/pubmed/23597113
http://dx.doi.org/10.1186/ar4215