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[(18)F]DPA-714 as a biomarker for positron emission tomography imaging of rheumatoid arthritis in an animal model

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic disease, affecting 0.5 to 1% of adults in industrialized countries, in which systemic inflammation and synovitis drive joint destruction. [(18)F]DPA-714 is a specific tracer of the 18 kDa translocator protein (TSPO), which is overexpressed on acti...

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Detalles Bibliográficos
Autores principales: Pottier, Géraldine, Bernards, Nicholas, Dollé, Frédéric, Boisgard, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060384/
https://www.ncbi.nlm.nih.gov/pubmed/24621017
http://dx.doi.org/10.1186/ar4508