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Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis

INTRODUCTION: Early diagnosis of and subsequent monitoring of therapy for rheumatoid arthritis (RA) could benefit from detection of (sub)clinical synovitis. Imaging of (sub)clinical arthritis by targeting the translocator protein (TSPO) on activated macrophages is feasible using (R)-[(11)C] PK11195-...

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Detalles Bibliográficos
Autores principales: Gent, Yoony YJ, Weijers, Karin, Molthoff, Carla FM, Windhorst, Albert D, Huisman, Marc C, Kassiou, Michael, Jansen, Gerrit, Lammertsma, Adriaan A, van der Laken, Conny J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060541/
https://www.ncbi.nlm.nih.gov/pubmed/24625077
http://dx.doi.org/10.1186/ar4509