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Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells

Scleroderma (systemic sclerosis; SSc) is characterised by fibrosis of the skin and internal organs in the context of autoimmunity and vascular perturbation. Overproduction of extracellular matrix components and loss of specialised epithelial structures are analogous to the process of scar formation...

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Detalles Bibliográficos
Autores principales: Gilbane, Adrian J, Denton, Christopher P, Holmes, Alan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060542/
https://www.ncbi.nlm.nih.gov/pubmed/23796020
http://dx.doi.org/10.1186/ar4230