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Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells
Scleroderma (systemic sclerosis; SSc) is characterised by fibrosis of the skin and internal organs in the context of autoimmunity and vascular perturbation. Overproduction of extracellular matrix components and loss of specialised epithelial structures are analogous to the process of scar formation...
Autores principales: | Gilbane, Adrian J, Denton, Christopher P, Holmes, Alan M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060542/ https://www.ncbi.nlm.nih.gov/pubmed/23796020 http://dx.doi.org/10.1186/ar4230 |
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