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MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc
INTRODUCTION: Degeneration of the intervertebral disc (IVD) is characterized by marked degradation and restructuring of the annulus fibrosus (AF). Although several matrix metalloproteinases (MMPs) have been found to be more prevalent in degenerate discs, their coordination and function within the co...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060574/ https://www.ncbi.nlm.nih.gov/pubmed/23621950 http://dx.doi.org/10.1186/ar4224 |