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Ca(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequences

The cardiac voltage gated Ca(2+) current (I(Ca)) is critical to the electrophysiological properties, excitation-contraction coupling, mitochondrial energetics, and transcriptional regulation in heart. Thus, it is not surprising that cardiac I(Ca) is regulated by numerous pathways. This review will f...

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Detalles Bibliográficos
Autores principales: Bers, Donald M., Morotti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060732/
https://www.ncbi.nlm.nih.gov/pubmed/24987371
http://dx.doi.org/10.3389/fphar.2014.00144