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Combination of 9-aminoacridine with Campath-1H provides effective therapy for a murine model of adult T-cell leukemia

BACKGROUND: Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy of CD4(+)CD25(+) lymphocytes caused by human T-cell lymphotropic virus type 1. While much progress has been made in understanding the mechanisms of cellular dysregulation, the prognosis for aggressive ATL still remains poor...

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Detalles Bibliográficos
Autores principales: Ju, Wei, Zhang, Meili, Petrus, Michael, Maeda, Michiyuki, Pise-Masison, Cynthia A, Waldmann, Thomas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060757/
https://www.ncbi.nlm.nih.gov/pubmed/24890041
http://dx.doi.org/10.1186/1742-4690-11-43