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The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1

BACKGROUND: Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of Sfrp1 expression is observed in breast cancer. The molecular mechanisms by which obesity contributes to breast tumorigenesis are not well defined, but involve increased in...

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Detalles Bibliográficos
Autores principales: Gauger, Kelly J, Bassa, Lotfi M, Henchey, Elizabeth M, Wyman, Josephine, Ser-Dolansky, Jennifer, Shimono, Akihiko, Schneider, Sallie S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060881/
https://www.ncbi.nlm.nih.gov/pubmed/24885183
http://dx.doi.org/10.1186/1476-4598-13-117