Cargando…
The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1
BACKGROUND: Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of Sfrp1 expression is observed in breast cancer. The molecular mechanisms by which obesity contributes to breast tumorigenesis are not well defined, but involve increased in...
Autores principales: | Gauger, Kelly J, Bassa, Lotfi M, Henchey, Elizabeth M, Wyman, Josephine, Ser-Dolansky, Jennifer, Shimono, Akihiko, Schneider, Sallie S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060881/ https://www.ncbi.nlm.nih.gov/pubmed/24885183 http://dx.doi.org/10.1186/1476-4598-13-117 |
Ejemplares similares
-
Mice Deficient in Sfrp1 Exhibit Increased Adiposity, Dysregulated Glucose Metabolism, and Enhanced Macrophage Infiltration
por: Gauger, Kelly J., et al.
Publicado: (2013) -
Loss of sfrp1 promotes ductal branching in the murine mammary gland
por: Gauger, Kelly J, et al.
Publicado: (2012) -
SFRP1 reduction results in an increased sensitivity to TGF-β signaling
por: Gauger, Kelly J, et al.
Publicado: (2011) -
Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44(high)/cd24(low )population which is invasive and resistant to anoikis
por: Gauger, Kelly J, et al.
Publicado: (2009) -
Sfrp Controls Apicobasal Polarity and Oriented Cell Division in Developing Gut Epithelium
por: Matsuyama, Makoto, et al.
Publicado: (2009)