The Human Orphan Nuclear Receptor Tailless (TLX, NR2E1) Is Druggable

Nuclear receptors (NRs) are an important group of ligand-dependent transcriptional factors. Presently, no natural or synthetic ligand has been identified for a large group of orphan NRs. Small molecules to target these orphan NRs will provide unique resources for uncovering regulatory systems that i...

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Detalles Bibliográficos
Autores principales: Benod, Cindy, Villagomez, Rosa, Filgueira, Carly S., Hwang, Peter K., Leonard, Paul G., Poncet-Montange, Guillaume, Rajagopalan, Senapathy, Fletterick, Robert J., Gustafsson, Jan-Åke, Webb, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060991/
https://www.ncbi.nlm.nih.gov/pubmed/24936658
http://dx.doi.org/10.1371/journal.pone.0099440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060991/
https://www.ncbi.nlm.nih.gov/pubmed/24936658
http://dx.doi.org/10.1371/journal.pone.0099440

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