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The Human Orphan Nuclear Receptor Tailless (TLX, NR2E1) Is Druggable
Nuclear receptors (NRs) are an important group of ligand-dependent transcriptional factors. Presently, no natural or synthetic ligand has been identified for a large group of orphan NRs. Small molecules to target these orphan NRs will provide unique resources for uncovering regulatory systems that i...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060991/ https://www.ncbi.nlm.nih.gov/pubmed/24936658 http://dx.doi.org/10.1371/journal.pone.0099440 |