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Association between DNMT3A Mutations and Prognosis of Adults with De Novo Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis

BACKGROUND: DNA methyltransferase 3A (DNMT3A) mutations were considered to be independently associated with unfavorable prognosis in adults with de novo acute myeloid leukemia (AML), however, there are still debates on this topic. Here, we aim to further investigate the association between DNMT3A mu...

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Detalles Bibliográficos
Autores principales: Tie, Ruxiu, Zhang, Tiansong, Fu, Huarui, Wang, Limengmeng, Wang, Yebo, He, Ying, Wang, Binsheng, Zhu, Ni, Fu, Shan, Lai, Xiaoyu, Shi, Jimin, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061003/
https://www.ncbi.nlm.nih.gov/pubmed/24936645
http://dx.doi.org/10.1371/journal.pone.0093353