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Targeted Next-Generation Sequencing at Copy-Number Breakpoints for Personalized Analysis of Rearranged Ends in Solid Tumors

BACKGROUND: The concept of the utilization of rearranged ends for development of personalized biomarkers has attracted much attention owing to its clinical applicability. Although targeted next-generation sequencing (NGS) for recurrent rearrangements has been successful in hematologic malignancies,...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Kyoung, Park, Won Cheol, Lee, Kwang Man, Hwang, Hai-Li, Park, Seong-Yeol, Sorn, Sungbin, Chandra, Vishal, Kim, Kwang Gi, Yoon, Woong-Bae, Bae, Joon Seol, Shin, Hyoung Doo, Shin, Jong-Yeon, Seoh, Ju-Young, Kim, Jong-Il, Hong, Kyeong-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061055/
https://www.ncbi.nlm.nih.gov/pubmed/24937453
http://dx.doi.org/10.1371/journal.pone.0100089