Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by progressive cognitive decline associated with a featured neuropathology (neuritic plaques and neurofibrillary tangles). Several studies have implicated oxidative damage to DNA, DNA repair, and altered cell-cycle regulation in addition to cell death in AD...

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Detalles Bibliográficos
Autores principales: Silva, Aderbal R. T., Santos, Ana Cecília Feio, Farfel, Jose M., Grinberg, Lea T., Ferretti, Renata E. L., Campos, Antonio Hugo Jose Froes Marques, Cunha, Isabela Werneck, Begnami, Maria Dirlei, Rocha, Rafael M., Carraro, Dirce M., de Bragança Pereira, Carlos Alberto, Jacob-Filho, Wilson, Brentani, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061071/
https://www.ncbi.nlm.nih.gov/pubmed/24936870
http://dx.doi.org/10.1371/journal.pone.0099897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061071/
https://www.ncbi.nlm.nih.gov/pubmed/24936870
http://dx.doi.org/10.1371/journal.pone.0099897

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