mTOR inhibition and levels of the DNA repair protein MGMT in T98G glioblastoma cells

BACKGROUND: Glioblastoma multiforme (GBM), the most common and most aggressive type of primary adult brain tumour, responds poorly to conventional treatment. Temozolomide (TMZ) chemotherapy remains the most commonly used treatment, despite a large proportion of tumours displaying TMZ resistance. 60%...

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Detalles Bibliográficos
Autores principales: Smalley, Sarah, Chalmers, Anthony J, Morley, Simon J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061125/
https://www.ncbi.nlm.nih.gov/pubmed/24909675
http://dx.doi.org/10.1186/1476-4598-13-144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061125/
https://www.ncbi.nlm.nih.gov/pubmed/24909675
http://dx.doi.org/10.1186/1476-4598-13-144

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