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mTOR inhibition and levels of the DNA repair protein MGMT in T98G glioblastoma cells
BACKGROUND: Glioblastoma multiforme (GBM), the most common and most aggressive type of primary adult brain tumour, responds poorly to conventional treatment. Temozolomide (TMZ) chemotherapy remains the most commonly used treatment, despite a large proportion of tumours displaying TMZ resistance. 60%...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061125/ https://www.ncbi.nlm.nih.gov/pubmed/24909675 http://dx.doi.org/10.1186/1476-4598-13-144 |