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Mapracorat, a selective glucocorticoid receptor agonist, causes apoptosis of eosinophils infiltrating the conjunctiva in late-phase experimental ocular allergy

BACKGROUND: Mapracorat, a novel nonsteroidal selective glucocorticoid receptor agonist, has been proposed for the topical treatment of inflammatory disorders as it binds with high affinity and selectivity to the human glucocorticoid receptor and displays a potent anti-inflammatory activity, but seem...

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Detalles Bibliográficos
Autores principales: Baiula, Monica, Bedini, Andrea, Baldi, Jacopo, Cavet, Megan E, Govoni, Paolo, Spampinato, Santi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061172/
https://www.ncbi.nlm.nih.gov/pubmed/24959069
http://dx.doi.org/10.2147/DDDT.S62659