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TAT-LHRH conjugated low molecular weight chitosan as a gene carrier specific for hepatocellular carcinoma cells

To develop a chitosan-based nonviral gene carrier capable of delivering genes specifically into hepatoma cells, a bifunctional peptide composed of the TAT (transactivator of transcription) peptide and luteinizing hormone-releasing hormone (LHRH) was conjugated with low molecular weight chitosan, res...

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Detalles Bibliográficos
Autores principales: Liu, Lanxia, Dong, Xia, Zhu, Dunwan, Song, Liping, Zhang, Hailing, Leng, Xigang G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061174/
https://www.ncbi.nlm.nih.gov/pubmed/24959076
http://dx.doi.org/10.2147/IJN.S61392