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Altered glutamate cysteine ligase activity in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

Reductions in glutathione (GSH) levels have been shown to be associated with aging and the pathogenesis of a variety of diseases, including systemic lupus erythematosus (SLE). Glutamate cysteine ligase (GCL) catalyzes the first and rate-limiting step of GSH synthesis. In order to appraise the correl...

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Detalles Bibliográficos
Autores principales: SONG, WEIQING, YUAN, JIANGSHUI, ZHANG, ZONGLIANG, LI, LI, HU, LIHUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061188/
https://www.ncbi.nlm.nih.gov/pubmed/24944621
http://dx.doi.org/10.3892/etm.2014.1689