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JNK inhibitor SP600125 protects against lipopolysaccharide-induced acute lung injury via upregulation of claudin-4

Although in vitro studies have previously demonstrated that mitogen-activated protein kinases are important for the activation of transcription factors and the regulation of proinflammatory mediators, the function of c-Jun NH(2)-terminal kinase (JNK) in acute lung injury (ALI) remains to be fully el...

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Detalles Bibliográficos
Autores principales: ZHENG, YUELIANG, ZHANG, MEIQI, ZHAO, YIMING, CHEN, JIE, LI, BING, CAI, WENWEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061205/
https://www.ncbi.nlm.nih.gov/pubmed/24944614
http://dx.doi.org/10.3892/etm.2014.1684