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NF-κB inhibition alleviates carbon tetrachloride-induced liver fibrosis via suppression of activated hepatic stellate cells

An effective treatment for hepatic fibrosis is not available clinically. Nuclear factor (NF)-κB plays a central role in inflammation and fibrosis. The aim of the present study was to investigate the effect of an NF-κB inhibitor, BAY-11–7082 (BAY), on mouse liver fibrosis. The effects of BAY on hepat...

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Detalles Bibliográficos
Autores principales: WANG, FEI, LIU, SHUYUAN, DU, TAIPING, CHEN, HAO, LI, ZHIYONG, YAN, JINGWANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061207/
https://www.ncbi.nlm.nih.gov/pubmed/24944604
http://dx.doi.org/10.3892/etm.2014.1682