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High dosage of agmatine alleviates pentylenetetrazole-induced chronic seizures in rats possibly by exerting an anticonvulsive effect

The aim of the present study was to investigate the mechanism underlying the effects of different doses of agmatine in rats with chronic epilepsy. To generate chronic epilepsy models, rats pretreated with different doses of agmatine (20, 40 and 80 mg/kg) were intraperitoneally injected with pentylen...

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Detalles Bibliográficos
Autores principales: XU, HUIQIN, OU, FUYONG, WANG, PEI, NAREN, MANGDULA, TU, DONGPEI, ZHENG, RONGYUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061208/
https://www.ncbi.nlm.nih.gov/pubmed/24944600
http://dx.doi.org/10.3892/etm.2014.1711