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Arsenic trioxide induces apoptosis in the THP1 cell line by downregulating EVI-1

Acute leukemia is a malignant clonal hematopoietic stem cell disease. In the current study, the effects of arsenic trioxide (ATO) on the ecotropic viral integration site-1 (EVI-1) gene were investigated in the THP1 cell line. THP-1 cells were treated with different concentrations of ATO (0, 1, 3 and...

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Detalles Bibliográficos
Autores principales: ZHOU, LING-YUN, CHEN, FANG-YUAN, SHEN, LI-JING, WAN, HAI-XIA, ZHONG, JI-HUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061239/
https://www.ncbi.nlm.nih.gov/pubmed/24944602
http://dx.doi.org/10.3892/etm.2014.1716