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Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions

Tumours require a vascular supply to grow and can achieve this via the expression of pro-angiogenic growth factors, including members of the vascular endothelial growth factor (VEGF) family of ligands. Since one or more of the VEGF ligand family is overexpressed in most solid cancers, there was grea...

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Detalles Bibliográficos
Autores principales: Vasudev, Naveen S., Reynolds, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061466/
https://www.ncbi.nlm.nih.gov/pubmed/24482243
http://dx.doi.org/10.1007/s10456-014-9420-y