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uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells

In the present study, we investigated the effect of simultaneous downregulation of uPAR and cathepsin B (pUC), alone or in combination with radiation, on JNK–MAPK signaling pathway in regulating the migration of non-GICs (glioma-initiating cells) and GICs. The increase in the expression of p-JNK wit...

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Detalles Bibliográficos
Autores principales: Alapati, Kiranmai, Kesanakurti, Divya, Rao, Jasti S., Dasari, Venkata Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061617/
https://www.ncbi.nlm.nih.gov/pubmed/24699410
http://dx.doi.org/10.1016/j.scr.2014.02.008