NLRP3 promotes autophagy of urate crystals phagocytized by human osteoblasts

INTRODUCTION: Monosodium urate (MSU) microcrystals present in bone tissues of chronic gout can be ingested by nonprofessional phagocytes like osteoblasts (OBs) that express NLRP3 (nucleotide-binding domain and leucine-rich repeat region containing family of receptor protein 3). MSU is known to activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Allaeys, Isabelle, Marceau, François, Poubelle, Patrice E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061723/
https://www.ncbi.nlm.nih.gov/pubmed/24456929
http://dx.doi.org/10.1186/ar4365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061723/
https://www.ncbi.nlm.nih.gov/pubmed/24456929
http://dx.doi.org/10.1186/ar4365

Ejemplares similares