Ensemble analyses improve signatures of tumour hypoxia and reveal inter-platform differences

BACKGROUND: The reproducibility of transcriptomic biomarkers across datasets remains poor, limiting clinical application. We and others have suggested that this is in-part caused by differential error-structure between datasets, and their incomplete removal by pre-processing algorithms. METHODS: To...

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Detalles Bibliográficos
Autores principales: Fox, Natalie S, Starmans, Maud HW, Haider, Syed, Lambin, Philippe, Boutros, Paul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061774/
https://www.ncbi.nlm.nih.gov/pubmed/24902696
http://dx.doi.org/10.1186/1471-2105-15-170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061774/
https://www.ncbi.nlm.nih.gov/pubmed/24902696
http://dx.doi.org/10.1186/1471-2105-15-170

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