White Matter Loss in a Mouse Model of Periventricular Leukomalacia Is Rescued by Trophic Factors

Periventricular leukomalacia (PVL) is the most frequent cause of cerebral palsy and other intellectual disabilities, and currently there is no treatment. In PVL, glutamate excitotoxicity (GME) leads to abnormal oligodendrocytes (OLs), myelin deficiency, and ventriculomegaly. We have previously ident...

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Detalles Bibliográficos
Autores principales: Espinosa-Jeffrey, Araceli, Barajas, Socorro A. R., Arrazola, Alfonso R., Taniguchi, Alana, Zhao, Paul M., Bokhoor, Payam, Holley, Sandra M., Dejarme, Don P., Chu, Brian, Cepeda, Carlos, Levine, Michael S., Gressens, Pierre, Feria-Velasco, Alfredo, de Vellis, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061895/
https://www.ncbi.nlm.nih.gov/pubmed/24961618
http://dx.doi.org/10.3390/brainsci3041461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061895/
https://www.ncbi.nlm.nih.gov/pubmed/24961618
http://dx.doi.org/10.3390/brainsci3041461

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