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White Matter Loss in a Mouse Model of Periventricular Leukomalacia Is Rescued by Trophic Factors
Periventricular leukomalacia (PVL) is the most frequent cause of cerebral palsy and other intellectual disabilities, and currently there is no treatment. In PVL, glutamate excitotoxicity (GME) leads to abnormal oligodendrocytes (OLs), myelin deficiency, and ventriculomegaly. We have previously ident...
Autores principales: | Espinosa-Jeffrey, Araceli, Barajas, Socorro A. R., Arrazola, Alfonso R., Taniguchi, Alana, Zhao, Paul M., Bokhoor, Payam, Holley, Sandra M., Dejarme, Don P., Chu, Brian, Cepeda, Carlos, Levine, Michael S., Gressens, Pierre, Feria-Velasco, Alfredo, de Vellis, Jean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061895/ https://www.ncbi.nlm.nih.gov/pubmed/24961618 http://dx.doi.org/10.3390/brainsci3041461 |
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