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PKC–NF-κB are involved in CCL2-induced Na(v)1.8 expression and channel function in dorsal root ganglion neurons
CCL2 [chemokine (C–C motif) ligand 2] contributes to the inflammation-induced neuropathic pain through activating VGSC (voltage-gated sodium channel)-mediated nerve impulse conduction, but the underlying mechanism is currently unknown. Our study aimed to investigate whether PKC (protein kinase C)–NF...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062041/ https://www.ncbi.nlm.nih.gov/pubmed/24724624 http://dx.doi.org/10.1042/BSR20140005 |