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Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases

BACKGROUND: Common human diseases are caused by the complex interplay of genetic susceptibility as well as environmental factors. Due to the environment’s influence on the epigenome, and therefore genome function, as well as conversely the genome’s facilitative effect on the epigenome, analysis of t...

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Detalles Bibliográficos
Autores principales: Wilson, Gareth A, Butcher, Lee M, Foster, Holly R, Feber, Andrew, Roos, Christian, Walter, Lutz, Woszczek, Grzegorz, Beck, Stephan, Bell, Christopher G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062055/
https://www.ncbi.nlm.nih.gov/pubmed/24598577
http://dx.doi.org/10.1186/gm536