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Correcting for cell-type composition bias in epigenome-wide association studies

Recent epigenome-wide association studies have indicated a potential role for epigenetic variation in the etiology of complex human diseases. However, one major challenge is to distinguish true epigenetic variation from changes caused by differences in cellular composition between the disease and no...

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Detalles Bibliográficos
Autores principales: Lowe, Robert, Rakyan, Vardhman K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062059/
https://www.ncbi.nlm.nih.gov/pubmed/25031617
http://dx.doi.org/10.1186/gm540