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Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia

BACKGROUND: Aberrant DNA methylation is frequently found in human malignancies including acute myeloid leukemia (AML). While most studies focus on later disease stages, the onset of aberrant DNA methylation events and their dynamics during leukemic progression are largely unknown. METHODS: We screen...

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Detalles Bibliográficos
Autores principales: Sonnet, Miriam, Claus, Rainer, Becker, Natalia, Zucknick, Manuela, Petersen, Jana, Lipka, Daniel B, Oakes, Christopher C, Andrulis, Mindaugas, Lier, Amelie, Milsom, Michael D, Witte, Tania, Gu, Lei, Kim-Wanner, Soo-Zin, Schirmacher, Peter, Wulfert, Michael, Gattermann, Norbert, Lübbert, Michael, Rosenbauer, Frank, Rehli, Michael, Bullinger, Lars, Weichenhan, Dieter, Plass, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062060/
https://www.ncbi.nlm.nih.gov/pubmed/24944583
http://dx.doi.org/10.1186/gm551